This review article discussed power amplifiers in modern wireless transmission systems, clarifying the determinants and restrictions of the create of power amplifiers in 5G and beyond transmission systems. The important topics of power amplifier design were discussed, which included solid-state techniques contributing to building the basic building block of the amplifier, furthermore to techniques for building the electronic circuit topology, while clarifying the importance of techniques for improving efficiency and linearity. This paper contributed to highlighting optimization and manufacturing techniques, focusing on the determinants and advantages of each technology. And clarifying the research space for researchers with the aim of developing a power amplifier that is optimal for use in modern wireless communications systems.